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DPHARM: Disruptive Innovations

Date: Sep 16, 2025 - Sep 17, 2025

Location: Philadelphia, PA

The Most Advanced Conference to Modernize Clinical Research

The 15th Annual DPHARM® offers an unparalleled opportunity to hear senior clinical operations executives and innovative thought leaders unveil the latest innovations on modernizing clinical trials. 

DPHARM faculty challenge the clinical operations community to rethink how clinical research gets done to drive greater inclusivity and value for patients.

2025 First Keynotes Announced

R&D
Leadership

Ken Frazier, JD
Former CEO and Current Executive Chairman
​​​​​​​Merck

Geopolitical
​​​​​​​Impact on R&D

Scott Gottlieb, MD
23rd Commissioner of the FDA

Patient
Advocate

Victoria Gray
First CRISPR Gene Therapy
Recipient for SCD

State of Clinical Trial Operations

Kenneth Getz, MBA
Executive Director & Professor
Tufts CSDD, Tufts University School of Medicine

2025 Senior Clinical Operations Leadership

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Jennifer Sheller, MPH
SVP, Head of Global Clinical Trial Operations, Global Clinical Development
Merck

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Elspeth Carnan, PhD
VP, Head of Trial Delivery Support
BMS

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David Carruthers
VP, Biopharma R&D Clinical Operations
AstraZeneca

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Bernhard Glombitza, PhD
VP, Clinical Customer Engagement and Operations EMEA & LATAM
Bayer

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Nikki Amaratunge
VP, Clinical Development Operations, Head of Clinical Site Management
AbbVie

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Melika Davis
SVP, Global Head, Clinical Operations
BeiGene

AI Thought Leadership

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Syed Wassim Haider, PhD
Head of Business, IT Partnership for AI
Merck

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Youssef Idelcaid, MBA
​​​​​​​
Head of AI Research Center [ARC], Drug Development
Gilead Sciences

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Faisal M Khan, PhD
Corporate Vice President, AI and Analytics
Novo Nordisk

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Henry Wei, MD
Head of Development Innovation
Regeneron

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Subha Madhavan, PhD
VP, Head of AI/ML, Quantitative and Digital Sciences R&D
Pfizer

Patient Disruptors

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Yvonnne Florence
Patient Advocate

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Patrick Gee Sr, PhD, JLC
Patient Advocate, Founder & Chief Executive Hope Dealer
iAdvocate, Inc

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Sabina Kineen
Patient Advocate

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Barry Nelson
Patient Advocate

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Rucha Shah
Patient Advocate and Assistant Clinical Research Project Manager, ECOG-ACRIN Cancer Research Group

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Vivan Larsen
Associate Patient Recruitment & Retention Strategy Director,
Exelixis

Convening 1000+ Attendees

DPHARM 2024 featured senior clinical operation executives with industry and patient thought leadership, and technologists showcasing the latest innovations in clinical trials driving efficiencies in operational processes and reducing patient, site and physician obstacles to participating in research.​​​​​​​

DPHARM Idol Disrupt

DPHARM Idol Disrupt is a series of quick-fire presentations where you see bold and daring startups pitch their disruptive technologies to the most discerning judges. The Q&A provides amazing shared learnings on how to properly assess new technologies.

Congratulations to 2024 Winner, Power!

If you are interested in applying for a spot as a DPHARM Idol Disrupt 2025 presenter, email Meredith@tcfllc.org

DPHARM Commitment

  • DPHARM combines TED-style talks with fireside chats, quick fires, panels and demos presentations showcasing innovations from leading Pharma R&D practitioners and from other industries.
  • DPHARM underscores the promise and challenge of innovation in advancing drug development.
  • DPHARM features new models and collaborations to get therapeutics to patients faster.
  • DPHARM features the full spectrum of clinical research options and utilizes insights more appropriately.
  • DPHARM is dedicated to challenging creative solutions and finding a way to implement them.

2025 Sponsors

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